From Chicago:
I-65 South to I-70 to Keystone Avenue Exit. Take Keystone North to 38th Street. West on 38th Street to the Indiana State Fairgrounds (on right)

From Cincinnati:
I-74 East to I-465 North to I-70 to Keystone Avenue Exit. Take Keystone Avenue North to 38th Street. West on 38th to Indiana State Fairgrounds (on right).

From Louisville:
I-65 North to I-70 East to Keystone Avenue Exit. Take Keystone Avenue North to 38th Street. West on 38th to Indiana State Fairgrounds (on right).

From St. Louis:
I-70 East to Keystone Avenue exit. . Take Keystone Avenue North to 38th Street. West on 38th to Indiana State Fairgrounds (on right).

From Detroit, Lansing or Fort Wayne:
I-69 South to SR 37 South (Bindford Blvd) which will turn into Fall Creek Parkway. Stay on Fall Creek Parkway till you get to the Indiana State Fairgrounds (on right).